John Henry Hopkins Jr.

John Henry Hopkins Jr. (October 28, 1820 – August 14, 1891) was an American clergyman and hymnodist, most famous for composing the song “We Three Kings of Orient Are” in 1857 (even though it does not appear in print until his Carols aluminium drink bottle, Hymns and Song in 1863).

Hopkins was born in Pittsburgh, Pennsylvania, the son of John Henry Hopkins, an Episcopal bishop. Hopkins graduated from the University of Vermont with an A.B. in 1839, and then a Master’s Degree in 1845. After a stint as a journalist, he graduated from the General Theological Seminary in 1850, and became a deacon, author, illustrator, and designer. He was the seminary’s first music teacher from 1855 to 1857, composed several hymns, and edited the Church Journal.

He wrote words and music to his most famous hymn, “We Three Kings”, as part of a Christmas pageant for his nieces and nephews. It is suggested to have been written in 1857 but did not appear in print until his Carols, Hymns and Songs in 1863. His nephew, John Henry Hopkins III, is credited with the music for “I Sing a Song of the Saints of God”

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, a popular children’s hymn in the Episcopal Church.

Hopkins served as rector of Trinity Church in Plattsburgh, New York from 1872 to 1876 and of Christ Episcopal Church in Williamsport, Pennsylvania from 1876 to 1887. He delivered the eulogy at the funeral of President Ulysses S Grant in 1885, and died in Hudson, New York. He was buried next to his father at Bishop’s House, Rock Point, Burlington, Vermont. Hopkins’ nephew, Charles Filkins Sweet, wrote a biography of his uncle entitled A Champion of the Cross, Being the Life of John Henry Hopkins, S.T.D.

PTPRJ

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Receptor-type tyrosine-protein phosphatase eta is an enzyme that in humans is encoded by the PTPRJ gene.

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation best goalkeeper gloves 2014. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This PTP is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 (PLCG1) and Linker for Activation of T Cells (LAT)

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. This PTP was also found to dephosphorylate PDGF beta receptor, and may be involved in UV-induced signal transduction.

PTPRJ has been shown to interact with CTNND1.

Princess Eleonora of Savoy

Eleonora of Savoy (Eleonora Maria Teresa; 28 February 1728 – 14 August 1781) was a Savoyard princess, the eldest daughter of Charles Emmanuel III of Sardinia and his second wife Polyxena of Hesse-Rotenburg. She died unmarried.

Eleonora Maria Teresa di Savoia was the second child and eldest daughter of Charles Emmanuel III, King of Sardinia and his second wife, the German Polyxena of the Landgraviate of Hesse-Rotenburg. She was born at the Royal Palace of Turin, the city residence of the Savoyard royal family.

She received the forename of her maternal grandmother

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, Eleonore of Löwenstein-Wertheim-Rochefort.

Her maternal cousins included Victor Amadeus II, Prince of Carignano and his younger sister the future princesse de Lamballe, both of which were born at the court of Savoy Meat Tenderizer. Her paternal cousins included Ferdinand VI of Spain

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, who was king of Spain at the time of her birth.

She was born to a relatively happy marriage between her parents. Her paternal grandmother Anne Marie d’Orléans died in August 1728 when Eleonora was six months old.

Her mother died in 1735 when Eleonora was six. Thus she was the highest ranking female at the Savoyard court until the marriage of her brother, the future Victor Amadeus III to the Spanish Infanta Maria Antonietta in 1750.

Eleonora, and her sister Maria Luisa, were proposed as brides for Louis, Dauphin of France, eldest son of Louis XV of France who was their first cousin. The marriage never materialised due to marriage negotiations with the Spanish which led to the dauphin marrying Maria Teresa, an older sister of Maria Antonietta in 1744.

Her two nieces, Princesses Maria Giuseppina and Maria Teresa would later marry two son’s of Louis, Dauphin of France in 1771 and 1773 respectively.

The spinster princess died at the Castle of Moncalieri, Turin at the age of 53. She was buried in the Royal Basilica of Superga overlooking Turin. Her sister in law Maria Antonietta died at Moncalieri in 1785.

The Secret Life of the American Teenager

The Secret Life of the American Teenager (auch kurz nur Secret Life oder als Akronym auch TSLOTAT) ist eine US-amerikanische Teen-Drama-Serie, die vom 1. Juli 2008 bis zum 3. Juni 2013 auf ABC Family ausgestrahlt wurde. Die Serie besteht aus fünf Staffeln mit 121 Episoden und spielt an einer kalifornischen Highschool. Hauptthemen sind Sex, ungewollte Schwangerschaften und Beziehungen unter den Schülern.

Die Serie spielt an einer High School in Kalifornien, USA. Es geht vor allem um Sex, ungewollte Schwangerschaften und Beziehungen zwischen den Schülern. Als die Schülerin Amy Juergens nach den Ferien vom Band-Summercamp zurückkehrt, stellt sie fest, dass sie bei einem One-Night-Stand mit dem berüchtigten Schulcasanova Ricky schwanger geworden ist. Immer mehr bricht die heile Welt um sie auseinander. Dabei stellt sich heraus, dass jeder ihrer Mitschüler sein eigenes, oft geheimes Problem hat.

Die deutsche Synchronisation entstand nach einem Synchronbuch und unter der Dialogregie von Heidrun Bartholomäus durch die Synchronfirma Lavendelfilm.

Produziert wurde die Serie von Brenda Hampton.

Die Serie wurde erstmals am 1. Juli 2008 vom Kabelsender ABC Family in den USA ausgestrahlt. Da für die erste Staffel zuerst nur 11 Episoden und erst später die anderen 12 Episoden fertiggestellt wurden

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, teilte man die Staffel in zwei Teile

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. Ebenso wurde mit den folgenden Staffeln verfahren. Die zweite Staffel wurde vom 22. Juni 2009 bis zum 22. März 2010 von ABC Family ausgestrahlt. Auf demselben Sender lief von Juni 2010 bis Juni 2011 die dritte Staffel und von Juni 2011 bis Juni 2012 die vierte Staffel. Im Juni 2012 begann die Ausstrahlung der fünften und letzten Staffel, deren letzte Episode am 3. Juni 2013 gesendet wurde.

Teen Choice Awards

Die Serie wurde bei den Teen Choice Awards insgesamt 9 Mal nominiert und gewann zwei Auszeichnungen (2008: Beste Sendung des Sommers, 2009: Bester männlicher Darsteller (Daren Kagasoff alias Ricky)).

Sonstige Auszeichnungen

Außerdem wurde die Serie 2009 mit dem Gracie Allen Award in der Kategorie Outstanding Drama ausgezeichnet.

Im Jahr 2010 wurde The Secret Of The American Teenager für den People’s Choice Award nominiert.

Mit ihrer neuen TV-Serie berührt Erfolgsautorin Brenda Hampton („Eine himmlische Familie“) ein in den USA häufig tabuisiertes Thema – und sicher auch deshalb wurde „The Secret Life of the American Teenager“ beim US-Fernsehpublikum zum Dauerbrenner. Die TV-Kritik lobte die Serie vor allem für ihren Realismus und zeichnete die erste Staffel mit einem „Teen Choice Award“ aus.